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SCINT — CMU |
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Live cell assays for cell death, apoptosis, morphology. Cells on the top are control cells and cells on the bottom have been treated with 10% DMSO for 15 minutes to induce some level of cell death (seen in red overlap with blue). |
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Mission |
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Nanomaterials which are much smaller than the lengthscale of the cell have unlimited potential for application in cellular and medical therapies. Of paramount importance in the development of any nanomaterial is the inadvertent effect that it will have on human health. National agencies, particularly NIH and NSF, have responded to this ethical idea and reinforced in the research community the importance of understanding acute and chronic toxic effects of nanomaterials for whatever purpose. The goal of this center is two-fold: 1. Measure toxicity of nanomaterials which are intended for non-biological purposes. Toxicity here has a wide meaning since nanomaterials have such unique properties. We will examine both the short-term death of cells as well as any long term “chronic” effects such as reduced proliferation or change in cellular organization or function. 2. Initiate biological and medical utilization of nanomaterials through cellular characterization experiments. Many times, the design of a nanomaterial is to elicit a cellular response. We will provide the cellular and biophysical technology and expertise to partner with a development group to facilitate initial cell-nanomaterial interactions. |
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The Dahl Lab Pittsburgh Technology Center 700 Technology Dr. Pittsburgh, PA 15219 or Department of Chemical Engineering Carnegie Mellon University Pittsburgh, PA 15213 |
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To contact us: |
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Phone: 412-268-9609 |
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Sub-Cellular Interactions with Nanomaterial Technologies |